Japanese Center for the Validation of Alternative Methods
日本動物実験代替法検証センター
事務局：国立医薬品食品衛生研究所 安全性生物試験研究センター 薬理部 新規試験法評価室

JaCVAMとは

用語解説

※動物実験の３Rs

Reduction (of animal use); Refinement (to lessen pain or distress and to enhance animal well-being); and Replacement (of an animal test with one that uses non-animal systems or phylo-genetically lower species) (OECD GD34)

※動物実験代替法（Alternative test）

A test that: reduces the numbers of animals required; refines procedures to lessen or eliminate pain or distress to animals, or enhance animal well-being; or uses non-sentient material in replacement for conscious living vertebrates (OECD GD34)

※バリデーション（Validation）

The process by which the reliability and relevance of a particular approach, method, process or assessment is established for a defined purpose (OECD　GD34)

※Peer Review

A documented critical review of a specific scientific work product or products, which is conducted by experts who are independent of the experts who performed the original work but who are collectively comparable in technical expertise (OECD GD34)