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Abbreviations

※List of abbreviation (Test method)
No. abbreviated word official name
01 Vitrolife-skinTM Reconstructed human tissue (developed in Japan; Vitrolife-SkinTM) cytotoxicity assay
02 3T3 NRU In Vitro 3T3 NRU  (neutral red uptake)Phototoxicity Test
03 Yeast-RBC assay Combination of yeast growth and hemolysis testing as alternative phototoxicity test
04 ROS ROS (reactive oxygen species) assay
05 LLNA Local lymph node assay (LLNA)
06 rLLNA Reduced LLNA (rLLNA)
07 LLNA:DA LLNA:DA (LLNA modified by Daicel based on ATP content)
08 LLNA:BrdU-ELISA LLNA:BrdU-ELISA (Enzyme-Linked Immunosorbent Assay)
09 h-CLAT in vitro Human cell line activation test (h-CLAT) for alternative skin sensitization assay
10 DPRA in vitro Direct peptide reactivity assay (DPRA) for alternative skin sensitization assay
11 KeratinoSense in vitro KeratinoSense assay for alternative skin sensitization assay
12 IL-8 Luc assay in vitro IL-8 Luc assay for alternative skin sensitization assay
13 LabCyte EPI-MODEL24 Alternative skin irritation test method using Reconstructed human tissue (developed in Japan; LabCyte EPI-MODEL24) 
14 EPISKIN, EpiDerm, SkinEthic alternative skin irritation test method using Reconstructed human tissue (EPSKIN, EpiDerm, SkinEthic)  
15 BCOP Bovine corneal opacity and permeability (BCOP) test method
16 ICE Isolated chicken eye (ICE) test method
17 FL Fluorescein Leakage Test Method
18 CM Cytosensor microphysiometer test
19 STE Short Time Exposure In Vitro Test Method
20 SIRC-CVS Cytyotoxicity test: the rabbit cornea-derived cell line (SIRC-CVS) assay
21 MATREX Cytyotoxicity test: Reconstructed human tissue (developed in Japan; MATREX) 
22 EpiOcular-EIT Reconstructed coreal tissue assay (EpiOcular-EIT)
23 Vitrigel-EIT Collagen gel (Vitrigel)-eye irritation test (EIT)
24 OECD TG No.405 OECD Guidelines for the Testing of Chemicals, Section 4  /  Test No. 405: Acute Eye Irritation/Corrosion
25 LabCyte CORNEA-MODEL-EIT In vitro eye irritation test using Human Corneal Tissue (Model:LabCyte CORNEA-MODEL24)
26 ER-STTA Estrogen receptor-stably transfected transactivation assay (ER-STTA) for the screening of chemicals
27 BG1Luc ERTA BG1Luc estrogen receptor transactivation assay (ERTA) for the screeing of agonistic and anti-agonistic activity of chemicals
28 CCi CCi MCF-7 assay for the screening of estrogenic and anti-estrogenic activity of chemicals
29 MELN MELN (derived from MCF-7) cell assay for the screening of estrgenic and anti-estrogenic activity of chemicals
30 AR-Ecoscreen AR-EcoScreen (the cell line expressing androgen receptor) assay for the screening of androgenic activity of chemicals
31 Hand1-Luc Hand1-Luc Embryonic Stem Cell Test (Hand1-Luc EST)
32 CYP induction method  Cytochrome P-450 induction based metabolic-competent model system 
33 Bhas Bhas 42 cell transformation assay
34 SHE Syrian hamster embryo (SHE) cell transformation assay
35 Balb BALB/c 3T3 cell transformation assay
36 In vitro PBMC in vitro pyrogen test method

※List of abbreviation
No. abbreviated word official name
01 COLIPA European Cosmetic,Toiletry and Perfumery Association
02 EURL ECVAM European Union Reference laboratory for Alternatives to Animal Testing
03 ICATM International Cooperation on Alternative Test Methods 
04 ICCVAM Interagency Coordinating Committee on the Validation of Alternative Methods
05 JaCVAM Japanese Center for the Validation of Alternative Methods
06 JEMS The Japanese Environmental Mutagen Society 
07 JSAAE Japanese Society for Alternatives to Animal Experiments 
08 KoCVAM Korean Center for the Validation of Alternative Method
09 MFDS Ministry of Food and Drug Safety, a government department in Korea
10 NEDO New Energy and Industrial Technology Development Organization
11 NICEATM NTP Interagency Center for the Evaluation of Alternative Toxicological Methods
12 OECD Organisation for Economic Co-operation and Development
13 Ph. Eur. Pharmacopoea Europaea
14 METI Ministry of Economy, Trade and Industry
15 MHLW Ministry of Health, Labour and Welfare
16 NIHS   National Institute of Health Sciences
17 JPMA  Japan Pharmaceutical Manufacturers Association
18 MAFF The Ministry of Agriculture, Forestry and Fisheries of Japan

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