Japanese Center for the Validation of Alternative Methods
Office : New Testing Method Assessment, Division of Pharmacology,
National Biological Safety Research Center (NBSRC),
National Institute of Health Sciences (NIHS)

JaCVAM Activities

JaCVAM Statements

【NEW】Skin sensitization test (LLNA-BrdU)

• JaCVAMStatement on the LLNA: BrdU-ELISA for skin sensitization testing (927 KB)
  03_002_13.pdf　

Skin irritation test(EPISKIN)

• JaCVAM Statement on the in vitro tests for skin irritation(250 KB)
  04_001_08.pdf　

Isolated Chiken Eye Test

• JaCVAM Statement on in vitro ocular toxicity test methods for identifying ocular corrosive and severe irritants: Isolated Chiken Eye Test Method (472 KB)
  05_001_08.pdf　

Bovine Corneal Opacity and Permeability Test

• JaCVAM Statement on in vitro ocular toxicity test methods for identifying ocular corrosive and severe irritants: Bovine Corneal Opacity and Permeability Test Method (466 KB)
  05_002_08.pdf　

Reconstructed human tissue test made in Japan:Vitrolife-Skin

• JaCVAM Statement on the Vitrolife-SkinTM,a3-dimensional cultured skin model for skin corrosivity testing(954KB)
  01_001_05_en.pdf　

Skin sensitization test (LLNA-DA)

• JaCVAMStatement on the LLNA-DA for skin sensitization testing(506KB)
  03_001_01_en.pdf